INSPIRED- Agricultural University of Athens (AUA)

The INSPIRED AUA is part of the Pan­Hellenic consortium “INSPIRED-The National Research Infrastructures on Integrated Structural Biology, Drug Screening Efforts and Drug Target Functional Characterization” (Grant MIS 5002550), which is implemented under the Action “Reinforcement of the Research and Innovation Infrastructure”, funded by the Operational Programme “Competitiveness, Entrepreneurship and Innovation” (Grant NSRF 2014–2020) and co-financed by Greece and the European Union (European Regional Development Fund). The INSPIRED AUA has facilities for X-ray crystal structure determination of biomolecules as well as small molecules. The center is a collaboration between Genetics and Physics Laboratories in the area of Structural Biology.

Service/Technology at INSPIRED-A.U.A

The INSPIRED-A.U.A is part of the Instruct-HL National Instruct Centre in Greece and provides support for the production, purification, biophysical characterization and crystallization of proteins and small molecules. It is accessible to both internal (Instruct-HL) and external research groups.

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Contact Info

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Visitor Information

The Agricultural University of Athens (A.U.A.) campus is located in the edge of the Ancient Site of Kerameikos and can be easily reached by car, bus or train. We are located in the Hassiotis building in the A.U.A. campus.


Scientific Contacts

Elias Eliopoulos

Professor

Kostas Bethanis

Assistant Professor

Admin Contacts

Athena Andreou

Associated Researcher

Elias Christophorides

Associated Researcher

Louis Papageorgiou

Associated Researcher


Publications


  1.  

    Structural and evolutionary insights within the polysaccharide deacetylase gene family of Bacillus anthracis and Bacillus cereus. Genes Andreou A., Giastas P., Christoforides E. and Eliopoulos E.E. PMID:30065210 ,

  2.  

    Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors. Biochemistry Giastas P., Andreou A., Papakyriakou A., Koutsioulis D., Balomenou S., Tzartos S.J., Bouriotis V. and Eliopoulos E.E. PMID:29257674 ,

  3.  

    The putative polysaccharide deacetylase Ba0331: cloning, expression, crystallization and structure determination. Acta Crystallogr F Struct Biol Commun Andreou A., Giastas P., Arnaouteli S., Tzanodaskalaki M., Tzartos S.J., Bethanis K., Bouriotis V. and Eliopoulos E.E. PMID:30065210 ,

  4. Structural studies of the inclusion compounds of α-naphthaleneacetic acid in heptakis(2,6-di-O-methyl)-β-Cyclodextrin and heptakis(2,3,6-tri-O-methyl)-β-Cyclodextrin by X-ray crystallography and molecular dynamics. Journal of Inclusion Phenomena and Macrocyclic Chemistry Bethanis, K., Christoforides, E., Tsorteki, F., Fourtaka K. and Mentzafos D.

  5.  

    Crystal structure of the inclusion complex of cholesterol in β-cyclodextrin and molecular dynamics studies. Beilstein Journal of Organic Chemistry Christoforides, E., Papaioannou A. and Bethanis K. PMID:29719578 ,

  6.  

    Crystal structures and molecular dynamics studies of the inclusion compounds of β-citronellol in β-cyclodextrin, heptakis(2,6-di-O-methyl)-β-cyclodextrin and heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin. Journal of Molecular Structure Fourtaka, K., Christoforides, E., Mentzafos D. and Bethanis K.

  7.  

    Structural studies of the inclusion complexes of the (+)- and (−)-borneol enantiomers in α- and β-cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry Christoforides, E., Mentzafos, D. and Bethanis, K.

  8.  

    Structural study of the inclusion compounds of thymol, carvacrol and eugenol in β-cyclodextrin by X-ray crystallography. Journal of Inclusion Phenomena and Macrocyclic Chemistry Bethanis, K., Tzamalis, P., Tsorteki, F., Kokkinou, A., Christoforides, E. and Mentzafos, D.

  9.  

    Convergence study of a Schrödinger-equation algorithm and structure-factor determination from the wavefunction. Acta Crystallographica A Bethanis K, Tzamalis P, Hountas A and Tsoucaris G. PMID:11961288 ,

  10.  

    Inclusion compounds of plant growth regulators in cyclodextrins. V. 4-Chlorophenoxyacetic acid encapsulated in beta-cyclodextrin and heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin. Acta Crystallographica B Bethanis K, Tzamalis P, Hountas A and Tsoucaris G. PMID:18560161 ,

  11.  

    The crystallographic symmetry test for the correctness of a set of phases. Acta Crystallographica A Tzamalis P, Bethanis K, Hountas A and Tsoucaris G. PMID:12496459 ,

  12.  

    Ab initio determination of a crystal structure by means of the Schrödinger equation. Acta Crystallographica A Bethanis K, Tzamalis P, Hountas A and Tsoucaris G. PMID:11961288 ,

Address

Agricultural University of Athens

Iera Odos 78, Athens 118 55

Greece

Scientific Contact

Professor Eliopoulos Elias
Genetics Laboratory
School of Applied Biology and Biotechnology
Agricultural University of Athens

Phone: 0030 210 5294223

Fax: 0030 210 5294374

Email: eliop@aua.gr
 

Admin Contact

Post-doc Christoforides Elias
Physics Laboratory
School of Applied Biology and Biotechnology
Agricultural University of Athens

Phone: 0030 210 5294225

Fax: 0030 210 5294233

Email: el_chr@aua.gr